Sharing the benefits in IBD
نویسندگان
چکیده
منابع مشابه
A renewal theory approach to IBD sharing.
A long genomic segment inherited by a pair of individuals from a single, recent common ancestor is said to be identical-by-descent (IBD). Shared IBD segments have numerous applications in genetics, from demographic inference to phasing, imputation, pedigree reconstruction, and disease mapping. Here, we provide a theoretical analysis of IBD sharing under Markovian approximations of the coalescen...
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Interbreeding between ancestors of humans and other hominins outside of Africa has been studied intensively, while their common history within Africa still lacks proper attention. However, shedding light on human evolution in this time period about which little is known, is essential for understanding subsequent events outside of Africa. We investigate the genetic relationships of humans, Neand...
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For more information about UCLan’s research in this area go to http://www.uclan.ac.uk/researchgroups/ and search for . For information about Research generally at UCLan please go to http://www.uclan.ac.uk/research/ All outputs in CLoK are protected by Intellectual Property Rights law, including Copyright law. Copyright, IPR and Moral Rights for the works on this site are...
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Over the past decade, clinical investigators and sponsors have shown increased interest in conducting clinical trials and other healthrelated research in resource-poor settings, notably Asia, Africa and South America. This move to poorer countries can bring many benefits: personnel costs are lower, and it is easier to recruit participants and to implement placebo-controlled trials that produce ...
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We present an analysis of the costs and benefits of load sharing of parallel jobs in the computational grid. We begin with a workload generation model that captures the essential properties of parallel jobs and use it as input to a grid simulation model. Our experiments are performed for both homogeneous and heterogeneous grids. We measured average job slowdown with respect to both local and re...
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ژورنال
عنوان ژورنال: Science-Business eXchange
سال: 2008
ISSN: 1945-3477
DOI: 10.1038/scibx.2008.471